This research is mainly to explore the thymus transplantation ' s effect on immunity function of patient associated with malignant tumor 本研究的目的就是探讨胸腺移植对恶性肿瘤患者免疫功能的影响。
Conclusions in the thymus transplantation patients associated with malignant tumor , the contents of iga , igm and igg increased significantly after transplantation 3 and 6 months . thymus transplantation can remarkably improve immunity function of patients associated with malignant tumor 结论恶性肿瘤患者胸腺移植术后,于第3 , 6个月的igg , igm , lga含量明显高于术前,胸腺移植能明显改善恶性肿瘤患者的免疫功能。
Igg , igm , iga are produced by b cell , in the course of b cell ' s activation , it needs nk c ell ' s assistant . before thymus transplantation , the patient associated with tumor has fewer th cell and its function recedes , so b cell ' s activation was suffocated and the ability of producing ig was weak Igg , igm , iga由b细胞产生,而b细胞在活化的过程中,需要th细胞的辅助,胸腺移植前,由于癌症患者th细胞数量减少,功能低下,致使b细胞活化受阻,产生ig的能力低下。
After thymus transplantation , the embryo ' s thymus has trunk cell that comes from the embryo ' s yolk bag , embryo liver and marrow , it excretes a great deal of thymus hormone which change lymphocyte into mature t lymphocyte through multiplication and differentiation , then it help to turn b cell into serous cell , the quantity of the serous cell increases , the antibody that it produces also increases , that is the content of iga , igm and igg is increased 而移制胎儿胸腺后,由于胎儿胸腺内有来自胎儿卵黄囊、胚肝和骨髓的干细胞,并能分泌大量胸腺素,促进淋巴细胞在该处增殖、分化为成熟t淋巴细胞,继而辅助b细胞活化成为浆细胞,浆细胞数量增加,产生的抗体量增加,即igg , igm , iga含量增加。